Real life management of chronic urticaria: Multicenter and cross sectional study on patients and dermatologists in Iran
Alireza Firooz, AliAsghar Akhlaghi, Pejman Golbidi, Marzieh Pourjafari, Fahimeh Abdollahimajd, Hamideh Azimi, Mahnaz Banihashemi, Farshid Darvish Damavandi, Abdol Reza Erfani, Saeedeh Farajzadeh, Mohammadreza Ghassemi, Mehdi Gheisari, Khalilollah Hamedpour, Farhad Handjani, Seyed Ali Hashemi, Hamideh Herizchi, Fariba Iraji, Homa Jalili, Alireza Khatami, Vahideh Lajevardi, Parvin Mansouri, Heidar Masjedi, Pedram Mehrian, Saman Mohammadi, Azadeh Mohebbi, Nastaran Namazi, Mansour Nasiri Kashani, Afsaneh Radmehr, Farid Safar, Zahra Saffarian, Sara Saniee, Hassan Seirafi, Soheila Taheri, Mohammad Javad Yazdanpanah, Naghmeh Zaboli Nejad, Mahsa Naseri, Parisa Peiravi, Gholamreza Teymori
Abstract
Recently, advances in understanding the etiology of urticaria and updates of diagnostic and therapeutic management guidelines have drawn attention to chronic urticaria (CU) morbidity. The present study aimed to evaluate Iranian dermatologists’ practice and real life management of CU patients. A total of 35 dermatologists and 443 patients were included in the study. Number of female patients was 321 (72.5%). Mean (standard deviation) age of the study patients was 38 (13) years and the median (inter quartile range) of disease duration was 12 (6–48) months. Severity of patients’ symptoms was mild for 32.1%, moderate for 38.7%, severe for 18.8%, and 10.4% of them had no evident signs or symptoms. The most common diagnostic methods were physical examination (96.6%), differential blood count (83.5%), erythrocyte sedimentation rate (77.4%), and C-reactive protein (62.8%). The number of dermatologists prescribed nonsedating antihistamines (nsAH) in regular dose and high dose mono therapy were 26 (74%) and 6 (17%), respectively. About 66% of dermatologists were familiar with British Association of Dermatologists (BAD) guideline. The most common first-line treatment for CU by Iranian dermatologists was nonsedating antihistamines in regular or high doses. The real-life management of patients with CU in Iran was in accordance with the available practice guidelines.
Keywords: chronic urticaria, guidelines, real-life practice
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